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Continuous Manufacturing (Flow Chemistry)
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Through partnerships with our clients, WuXi STA has established an ever-evolving continuous manufacturing (flow chemistry) platform offering process development, non-GMP, and cGMP production services for projects from pre-clinical to commercial stage. Taking advantages of our rich experience built on hundreds of projects, and the modularization of our multi-purpose continuous manufacturing lines, we are able to offer the quick and economically viable solution to tackle the process challenges under conventional batch mode. 

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Selected reactions in our continuous manufacturing toolbox:
  • Low temperature metallo-organic reactions 
  • High temperature/pressure reactions
  • Continuous ozonolysis reactions
  • Oxidation involving the use of air/oxygen or peroxides 
  • Nitrogen rich reactions involving azides or hydrazine
  • Continuous photo reactions
  • Flow hydrogenation
  • Flow nitration
  • Enzymatic reactions using immobilized enzymes
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Large scale (> 1 metric ton (MT)) continuous manufacturing experience on selected reactions
Low temperature metallo-organic reactions
  • Deprotonation and Michael addition
  • Lithiation and methylation
High temperature/pressure reactions
  • Cope Elimination
  • Amination
Photo chemistry
  • Photo halogenation
Oxidation
  • Aerobic oxidation
  • Swern oxidation
Others
  • Amide coupling
  • Hydrogenation
  • Cyanidation
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